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Journal of the Korean Society of Neonatology 2001;8(1):166-170.
Published online May 1, 2001.
A Case of Koebner Variant of Epidermolysis Bullosa Simplex.
Seong Joon Lim, Soon Pil Jung, In Seok Lim, Dong Keun Lee, Byung Hoon Yoo
Department of Pediatrics, College of Medicine, Chungang University, Seoul, Korea.
부자간에 발생한 Koebner형 전신성 단순성 수포성 표피박리증 1례
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Abstract
Epidermolysis bullosa simplex (EBS), characterized by a cleavage plane through basal keratinocytes, is caused by a mutation of the genes encoding keratin 5 and 14. It is often regarded as the least severe form of Epidermolysis bullosa. In 1886, Koebner described the seasonal blisterings predominantly on the palms and soles but occurring on the other sites of friction with clothes as well. His name is often used to describe EBS with the generalized blisterings. We have experienced a case of Koebner variant of EBS in a two-day old male neonate whose father had the same EBS. Hereby, we report his clinical, histopathological findings with a brief review of the literature.
Key Words: Epidermolysis bullosa simplex, Koebner variant, Neonate
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