A case of Adenovirus Infection in the Neonate.

Kim,  Ee Kyung; Lee,  Hee Eun; Ko,  June Tae; Park,  June Dong; Kim,  Beyong Il; Lee,  Hoan Jong; Choi,  Jung Hwan; Yun,  Chong Ku; Kim,  Jong Je; Chi,  Je Geun; Lee,  Jeong Mi

Case Report

Journal of the Korean Society of Neonatology 1997;4(1):67-71.
Published online January 1, 2001.

A case of Adenovirus Infection in the Neonate.

Ee Kyung Kim, Hee Eun Lee, June Tae Ko, June Dong Park, Beyong Il Kim, Hoan Jong Lee, Jung Hwan Choi, Chong Ku Yun, Jong Je Kim, Je Geun Chi, Jeong Mi Lee

¹Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
²Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
³Department of Pediatrics, Sowha Children's Hospital, Seoul, Korea.

Abstract

Adenovirus is an important etiologic agent in the pediatric population with fever and respiratory disease, but in newborn period, it has been known rarely to cause illness. But, its tendency of dissemination in immunocompromized host makes the neonate a high risk group of severe adenoviral infection. A newborn girl who presented with pneumonia, pulmonary hemorrhage, hepatitis, and disseminated intravascular coagulation continued to deteriorate in spite of the antibiotic therapy and maximal ventilatory support. The autopsy revealed adenoviral infection in the lung by electron microscopy. Adenoviral infection should be also suspected when a newborn infant has pneumonia, hepatitis, neurologic symptoms, and disseminated intravascular coagulation and especially his or her bacterial culture results are negative.

Key Words: Adenovirus; Neonate