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Neonatal Med > Volume 18(2); 2011 > Article
Journal of the Korean Society of Neonatology 2011;18(2):280-287.
DOI: https://doi.org/10.5385/jksn.2011.18.2.280    Published online November 25, 2011.
Association of Positive Ureaplasma in Gastric Fluid with Clinical Features in Preterm Infants.
Yu Jin Jung
Department of Pediatrics, Kosin University Gospel Hospital, Busan, Korea. hasaohjung@hanmail.net
The purpose of the present study was to determine the association of positive Ureaplasma urealyticum in gastric fluid with clinical features and outcomes in preterm infants.
Gastric fluid from the preterm infants was first aspirated within 30 minutes and cultured within 24 hours after birth to check for U. urealyticum. Infants were divided into two groups on the basis of the presence/absence of U. urealyticum.
U. urealyticum in gastric fluid was identified in 17 of 91 (19%) preterm infants. Compared with the negative U. urealyticum group, there were significantly higher percentage of infants with gestational age < or =30 weeks (P=0.020), higher Apgar score at 1 minute and 5 minutes (P=0.017 and P=0.048, respectively), and higher rate of vaginal delivery (P=0.000) in the positive U. urealyticum group. Although the incidence rate of bronchopulmonary dysplasia between the two groups was not different, the frequency of bronchopulmonary dysplasia without previous respiratory distress syndrome was significantly higher in the positive group (11%) than that in the negative group (1%) (P=0.030).
The detection of U. urealyticum in gastric fluid is more frequent in infants with gestational age < or =30 weeks. It can be helpful to predict the development of bronchopulmonary dysplasia without previous respiratory distress syndrome in preterm infants.
Key Words: Preterm infant, Ureaplasma urealyticum, Bronchopulmonary dysplasia


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