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Journal of the Korean Society of Neonatology 2010;17(1):109-115.
Published online May 1, 2010.
Two Cases of Neonatal Persistent Pulmonary Hypertension Treated by Veno-venous Extracorporeal Membrane Oxygenation (V-V ECMO).
Hee Joon Yu, Se In Sung, Jin Kyu Kim, Hyun Joo Seo, Seo Heui Choi, Hye Soo Yoo, So Yoon Ahn, Eun Sun Kim, Ji Hyuk Yang, June Huh, Yun Sil Chang, I Seok Kang, Tae Kook Jun, Won Soon Park
1Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wonspark@skku.edu
2Department of Thoracic & Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
정맥-정맥 도관 체외막형 산소섭취로 치료한 신생아의 지속성 폐동맥 고혈압증 2례
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2
Abstract
Persistent pulmonary hypertension in newborns (PPHN) is a disorder of the vascular transition from fetal to neonatal circulation. It results in cyanosis due to right-to-left shunting of the blood through the ductus arteriosus and/or foramen ovale manifesting as hypoxemic respiratory failure. We managed two cases of PPHN after meconium aspiration with high frequency oscillating ventilators and inhaled nitric oxide. They did not respond to conventional management. Veno-venous extracorporeal membrane oxygenation (ECMO) was provided, and ECMO weaning was possible resulting survivals in two cases. We report two PPHN cases, which were treated successfully with veno-venous ECMO for the first time in Korea.
Key Words: Persistent pulmonary hypertension of the newborn, Meconium aspiration syndrome, Respiratory failure, Veno-veno extracorporeal membrane oxygenation


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