A Study on Survival in the Very Low Birth Weight Infants Received Neonata Intensive Care in Two Years. |
Eun Kyung Lee, Jee Yeon Min, Yun Sil Chang, I Seok Kang, Won Soon Park, Mun Hyang Lee, Heung Jae Lee, Sei Yeul Oh, Suk Koo Lee, Hyun Hahk Kim, Hye Kyung Yoon, Bo Kyung Kim, Tae Gook Jun, Pyo Won Park |
1Department of Pediatrics, Ophthalmology, General Surgery, Radiology, Thoracic Surgery, College of Medicine, Sung Kyunkwan University, Samsung Medical Center, Seoul, Korea. 2Department of Ophthalmology, College of Medicine, Sung Kyunkwan University, Samsung Medical Center, Seoul, Korea. 3Department of General Surgery, College of Medicine, Sung Kyunkwan University, Samsung Medical Center, Seoul, Korea. 4Department of Radiology, College of Medicine, Sung Kyunkwan University, Samsung Medical Center, Seoul, Korea. 5Department of Thoracic Surgery, College of Medicine, Sung Kyunkwan University, Samsung Medical Center, Seoul, Korea. |
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Abstract |
PURPOSE Recent progress in neonatal intensive care has led to increased survival of infants weighing less than 1500 gm.
Many studies to declining sequelae of intensive care, addition to increasing survival, were made. So, we investigated particulary the relationship between survival and birth weight, gestational age, and factors associated with morbidities. METHOD The retrospecitve review of medical records was analyzed for 92 VLBW infants(birth weight <1,500gm) who were admitted to the neonatal intensive care unit of Samsung seoul hosptial from 1994 to 1996. We compared the outcomes of 32 VLBW infants between October 1994 and September 1995 (period I), with the outcomes of 60 VLBW infants between October 1995 and September 1996 (period II). RESULTS 1) The incidence of VLBW infants was 1.01% in period I and 1.55% in period II. The overall survival rate increased to 76.7% in period II, compared with 71.9% in period I. 2) By birth weight, the highest survival rate was 100% at 750gm in peeriod I, and 86.4% at 1000 to 1249gm in period II. The survival rate at birth weight 1000 to 1249 gm increased significantly in period II. According to gestational age, the highest was at 31-32 weeks(85.7%) in period I, and at 29-30 weeks(88.9%) in period II. 3) The male : female ratio was 1:1 in period I versus 1:1.07 in period II. There was no significant difference in sex and mode of delivery. 4) The most common major morbidity occurred in VLBW infants was respiratory distress syndrome (65.6% in period I, 53.3% in period II). 5) There was no difference of neonatal death rate during period I, while 2-3 days after birth was the highest(30.0%) during period II.
Major causes of death, during both periods, were infection and respiratory distress syndrome and/or its sequelae. CONCLUSION This report demonstrates marked increased survival rate than previous other reports and especially during period II. With increasing survival, more attention to neonatal sequelae, including chronic lung disease and neurodevelopmental delay, is required. |
Key Words:
Very low birth weight infant |
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