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Neonatal Med > Volume 25(1); 2018 > Article
Neonatal Medicine 2018;25(1):23-28.
DOI:    Published online February 28, 2018.
Clinical Implication of Surgically treated Abdominoperineal Soild Tumor in the Newborn : A Single-Center Experience.
Yong Hoon Cho, Soo Hong Kim, Hae Young Kim, Young Mi Han, Na Rae Lee, Mi Hye Bae, Kyung Hee Park, Shin Yun Byun
1Division of Pediatric Surgery, Department of Surgery, Pusan National University School of Medicine, Yangsan, Korea.
2Division of Neonatology, Department of Pediatrics, Pusan National University School of Medicine, Yangsan, Korea.
Abdominoperineal solid tumors presenting in neonates often require surgical intervention during the neonatal period. Although we report our single-center experience, this study would be meaningful to understand the clinical implications of these neoplasms.
We retrospectively reviewed and analyzed the clinical data and characteristics of 22 patients (≤28 days old) diagnosed with histopathologically confirmed abdominoperineal solid neoplasms (benign or malignant) after surgical resection.
The mean gestational age and postnatal age at the time of operation were 38.3±1.8 weeks and 13.5±8.3 days, respectively. Most patients (18/22, 81.8%) were diagnosed during antenatal care visits; however, 4 (18.2%) were identified after birth. The mean tumor size was 6.4×5.3 cm (3.5–17.0 cm), and tumors occurred most frequently within the sacrococcygeal region (8/22, 36.4%). Histopathologically, 14 patients (63.6%) demonstrated benign tumors and 8 (36.4%) demonstrated malignant tumors. Germ cell tumors and hepatoblastomas were the most commonly observed tumors. Fortunately, all patients showed a localized pattern of tumor involvement without distant metastasis. No recurrence or mortality was observed during the follow-up period (mean 66.4±44.2 months).
Abdominoperineal solid tumors occurring in neonates show variable clinical patterns during the antenatal and postnatal monitoring/screening periods. We conclude that aggressive and multidisciplinary approaches could achieve good clinical results in these patients.
Key Words: Abdominoperineal; Solid tumor; Newborn


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