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Neonatal Med > Volume 23(2); 2016 > Article
Neonatal Medicine 2016;23(2):121-126.
DOI: https://doi.org/10.5385/nm.2016.23.2.121    Published online May 31, 2016.
Enoxaparin Therapy for Arterial Thrombosis After Umbilical Cord Catheterization in Preterm Infants.
Yoon Joo Kim, Young Don Kim, Jae Hong Choi
Department of Pediatrics, Jeju National University School of Medicine, Jeju, Korea. cardios@hanmail.net
Abstract
The incidence of symptomatic thrombosis of umbilical arterial catheterization is 1-3%. Therapeutic options may include: using heparin or low molecular weight heparin, using a thrombolytic agent, or surgical thrombectomy. However, there are insufficient data to recommend any one treatment over the others. Recently, enoxaparin, a low molecular weight heparin, has emerged as a drug of choice for the treatment of neonatal thrombosis due to pharmacologic stability over unfractionated heparin or thrombolytic agents. We report a case of successful treatment of aortic thrombosis after umbilical arterial catheterization with enoxaparin in preterm infants.
Key Words: Preterm infants, Enoxaparin, Arterial thrombosis, Umbilical artery catheter


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