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Neonatal Med > Volume 22(1); 2015 > Article
Neonatal Medicine 2015;22(1):21-26.
DOI:    Published online February 28, 2015.
Presentation Time of Necrotizing Enterocolitis Diagnosed by Sonography according to Gestational Age.
So Hyun Kim, Joo Hyung Park, Chung Joon Moon, Gye Yeon Lim, So Young Kim
1Department of Pediatrics, School of Medicine, The Catholic University of Korea, Seoul, Korea.
2Department of Radiology, School of Medicine, The Catholic University of Korea, Seoul, Korea.
In this single center study, we assessed the timing of presentation of necrotizing enterocolitis (NEC) diagnosed by sonography according to the gestational age.
We retrospectively reviewed the medical records of 49 newborn patients who were diagnosed with NEC (modified Bell's stage II and higher according to abdominal sonography and simple abdominal radiography) and were admitted to the neonatal intensive care unit of St. Mary's Hospital between January 2008 and December 2012. Infants were grouped according to their gestational age (GA): Group I (GA <28 weeks), Group II (GA, 28-32 weeks), Group III (GA, 33-36 weeks), and Group IV (GA > or =37 weeks); early-onset NEC was considered when NEC developed at <14 days of age and late-onset NEC was considered when NEC developed at > or =14 days of age.
The number of infants in each group were: Group I (n = 16), Group II (n = 20), Group III (n = 11), and Group IV (n = 2). The mean age at diagnosis of NEC was: Group I (31.6 days), Group II (15.9 days), Group III (11.0 days), and Group IV (2.0 days). Early-onset NEC developed at a mean of 5.5 days of age, whereas late-onset NEC developed at a mean of 36.1 days of age.
Based on early sonographic diagnosis, infants with lower gestational ages developed NEC at a more advanced postnatal age as compared to more mature infants. However, further studies are needed to understand the etiology of this disease process.
Key Words: Newborn; Necrotizing enterocolitis; Ultrasonography; Diagnosis; Epidemiology


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